Founder & CEO, WearSynapse. For Better Care. Hyderabad, India.
Karthik Nagapuri, known as Zero, is the Founder and CEO of WearSynapse, a hands-free clinical AI that turns doctor and patient conversations into reviewed clinical notes. Emergent Ventures grantee, TEDx speaker and former Head of Selections and Alumni at Jagriti Yatra, based in Hyderabad, India.
Technology should democratize opportunity, not concentrate it.
Mission: build what should exist
I start companies where the need is obvious and the builders are missing. The next great company will not come from the usual postcodes, and the people it serves will not be an afterthought.
Start from zero. No inherited network, no borrowed playbook. First principles, then relentless shipping.
Build for a billion. Design for Bharat first, where cost, language and trust are the real constraints. What works here works anywhere.
Care is the product. At WearSynapse, technology earns its place only when it gives doctors time back and patients better care.
What I am building
Wear Synapse, Founder & CTO (Jan 2026-Present). Deeptech clinical intelligence — a privacy-first wearable for hospitals.
WearSynapse, StartupBharat, Jagriti Yatra, Draper University, Draper Startup House, Emergent Ventures (Mercatus Center), T-Hub, T-Works, Indian School of Business, EdVenture Park, Nexteen, LooCafé, Anurag University, Alien Innovations, Edodwaja Foundation, Gear Head Motors, Growth School, Starbuzz AI and Student Tribe.
A founder's journey
From a rural farming family in Telangana to building founder-first ecosystems across Bharat. The journey from village beginnings shaped my belief that the next unicorn can come from anywhere.
SafeBlock: CTO and Founder, an end-to-end crypto nominee system preventing digital asset loss.
LooCafé / Ixora Group: Head of Technology. "Most Innovative Company" by CII, UNDP Best Practice.
LiteraZe Society: Technical Lead, literacy and education initiatives (2019-2023).
FeatureIndia: Chief Technology Officer.
TextHappen Content: Senior Director of Operations.
Fellowships and recognition
Emergent Ventures India grantee (2022), Mercatus Center at George Mason University
Kairos Fellow (2023-24)
Suzuki Innovation Centre Fellow
25 Under 25 (2023), Stumagz and Telangana State Innovation Cell
Draper University Founder Program, Cohort 2 (2026)
Education
B.Tech in Artificial Intelligence, Anurag University.
TEDx: Building Integrated Communities with Zero Mindset
At TEDxCMRIT Hyderabad (2025), on the journey from rural villages to scaling national-scale initiatives. Watch the talk.
The paradox of being zero
"Sunya" means void, and paradoxically, the same word means universe, infinite energy. I chose to call myself Zero, not from lack of value or confidence, but from perspective. Read why.